When you think of fall foliage destinations, you probably don't think about Kansas. Most people would not associate the Sunflower State with fall color. Indeed, most of Kansas is prairie, not woodlands. That being said, there are some fall foliage locations in Kansas if you know where to look for them.
Many of the towns in the eastern third of the state have mature trees that were planted by the European Settlers and are still maintained today. Farther west, the trees begin to get sparse, but the Cottonwoods provide some nice yellow color against the blue Kansas sky.
I have found some great fall color at the Marais des Cygnes National Wildlife Refuge. Located between Kansas City and Fort Scott, this Wildlife Refuges preserves some beautiful stands of timber. In the fall, the colors can be gorgeous - although the vividness of the colors does depend on the weather.
While Kansas will never rival New England or Appalachia in terms of fall foliage, there is some color here if you are willing to get off the Interstate and look for it.
US 69 is a major highway that connects Kansas City with Southeastern Kansas. It runs right past the Marais des Cygnes Wildlife Area.